Receptor

Binding sites are a fundamental concept in molecular biology and biochemistry, crucial for understanding the interactions between biomolecules in various scientific experiments.
These specific regions on the surface of proteins, nucleic acids, or other macromolecules allow for the binding of ligands, substrates, or other molecules, enabling a wide range of biological processes and applications.
Researchers often investigate binding site properties, kinetics, and dynamics to elucidate molecular mechanisms, screen for potential drug candidates, or engineer novel biosensors and therapeutic agents, making binding site analysis a valuable tool in the scientific toolbox.

Epidermal Growth Factor Receptor VIII (EGFR VIII) is a mutant variant of the EGFR protein that is frequently observed in various types of cancers, particularly glioblastoma multiforme.
This receptor plays a crucial role in cell proliferation, survival, and migration, making it a valuable target for cancer research and drug development.
Researchers often utilize EGFR VIII in a wide range of scientific experiments, including cell signaling studies, therapeutic target identification, and the evaluation of novel cancer treatments, such as targeted therapies and immunotherapies.

Glucagon-Like Peptide-1 Receptor (GLP-1R) is a crucial target in metabolic and endocrine research, playing a central role in regulating glucose homeostasis and insulin secretion.
This membrane-bound receptor is commonly studied in preclinical models to investigate the mechanisms underlying type 2 diabetes, obesity, and related metabolic disorders, as well as to evaluate the efficacy of novel GLP-1R agonists as potential therapeutic interventions.
Researchers frequently employ GLP-1R-related protocols to assess receptor expression, signaling pathways, and the impact of pharmacological modulation on glucose and energy metabolism.

The IGF2R protein, also known as the insulin-like growth factor 2 receptor, is a key player in cellular signaling and growth regulation.
Widely used in various scientific experiments, the human IGF2R protein is a valuable tool for researchers studying topics such as cell proliferation, apoptosis, and embryonic development.
Owing to its critical role in essential biological processes, the IGF2R protein, human, is a commonly employed target for a range of applications, including protein-protein interaction studies, immunoassays, and cell-based assays.