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Contact Lenses

Contact lenses are medical devices worn on the surface of the eye, designed to correct vision, protect the eye, or serve cosmetic purposes.
They come in a variety of materials, designs, and prescriptions to meet the diverse needs of wearers.
These lenses can be used for everyday vision correction, specialty applications like sports or occupational use, or for enhanceing the appearance of the eyes.
Proper fitment, care, and usage are critical to ensure the safety and comfort of contact lens wearers.
Experienxe the latest advancements in contact lens technology and optimization with PubCompare.ai, your one-stop platform for revolutionizing contact lens research.

Most cited protocols related to «Contact Lenses»

The participants in the SICCA cohort have been enrolled since 2004 at five collaborating academically-based research groups, located in Argentina, China, Denmark, Japan and the United States, and directed from the University of California, San Francisco (12 (link)) (Table 1). Subsequently, additional research groups joined the SICCA project: in 2007, from the United Kingdom and in 2009, from India and two additional sites in the United States.
To be eligible for the SICCA registry, participants must be at least 21 years of age and have at least one of the following: symptoms of dry eyes or dry mouth; a previous suspicion or diagnosis of SS; elevated serum antinuclear antibodies (ANA), positive rheumatoid factor (RF), or anti-SSA/B; bilateral parotid enlargement in a clinical setting of SS; a recent increase in dental caries; or have diagnoses of rheumatoid arthritis or systemic lupus erythematosus and any of the above. The rationale for these eligibility criteria is that only patients with such characteristics would be evaluated for SS or considered for enrollment in a clinical trial designed to evaluate a potential therapeutic agent for SS. Therefore our classification criteria target individuals with signs and symptoms that may be suggestive of SS, not the general population.
Participants are recruited through local or national SS patient support groups, healthcare providers, public media, and populations served by all nine SICCA research groups. Exclusion criteria include known diagnoses of: hepatitis C, HIV, sarcoidosis, amyloidosis, active tuberculosis, graft versus host disease, autoimmune connective tissue diseases other than rheumatoid arthritis or lupus; past head and neck radiation treatment; current treatment with daily eye drops for glaucoma; corneal surgery in the last 5 years to correct vision; cosmetic eyelid surgery in the last 5 years; or physical or mental condition interfering with successful participation in the study. Contact lens wearers are asked to discontinue wear for 7 days before the SICCA examination. We do not exclude participants taking prescription drugs that may affect salivary or lacrimal secretion, but record their use and all other medications currently taken.
Publication 2012
Administration, Ophthalmic Amyloidosis Antibodies, Antinuclear Connective Tissue Diseases Contact Lenses Cornea Dental Caries Diagnosis Dry Eye Eligibility Determination Eyelids Glaucoma Graft-vs-Host Disease Head Health Personnel Hepatitis C virus Hypertrophy Lupus Erythematosus, Systemic Lupus Vulgaris Neck Operative Surgical Procedures Parotid Gland Patients Pharmaceutical Preparations Physical Examination Prescription Drugs Radiotherapy Rheumatoid Arthritis Rheumatoid Factor Sarcoidosis secretion Serum Therapeutics Tuberculosis Vision Xerostomia
Patients with normal eyelid and corneal anatomy were prospectively recruited from the Miami Veterans Affairs (VA) Healthcare System eye clinic between October 2013 and October 2017. Patients with scheduled appointments for regular check-ups, for new symptoms related to the eye, or for follow-up appointments, regardless of DE diagnosis, were included as potential participants.
Patients were excluded from participation if they had risk factors accounting for their dry eye symptoms, including: contact lens use, use of ocular medications other than artificial tears, history of refractive surgery, HIV, sarcoidosis, graft-versus host disease or a collagen vascular disease, presence of an active external ocular process, cataract surgery within the last 6 months, history of any glaucoma, or retinal surgery. Participants who did not speak and understand English well were also excluded. Informed consent was obtained from all subjects. Miami VA Institution Review Board approval was obtained to allow the prospective evaluation of subjects. The study was conducted in accordance to the principles of the Declaration of Helsinki and complied with the requirements of the United States Health Insurance Portability and Accountability Act.
In the original NPSI validation paper [8 (link)], the authors included only individuals with at least moderate levels of pain severity (visual analogue scale scores of ≥ 30mm out of 100mm), and for whom pain was due to peripheral or central nervous system injury as indicated by clinical history, laboratory data, and/or imaging. For ocular pain, there is currently no gold standard method to diagnose neuropathic ocular pain nor to verify ocular nervous system lesion. As such, in this paper, we took an inclusive approach, in order to provide a wide range of NPSI scores, and analyzed data from all individuals with reported eye pain, defined as a Numerical Rating Scale (NRS) score of ≥ 1 for average eye pain intensity during the past week.
Publication 2019
Blood Vessel Cataract Extraction Collagen Collagen Diseases Contact Lenses Cornea Diagnosis Dry Eye Ethics Committees, Research Eyelids Glaucoma Gold Graft-vs-Host Disease Inclusion Bodies Lubricant Eye Drops Neuralgia Operative Surgical Procedures Pain Pain, Eye Patient Appointments Patients Pharmaceutical Preparations Retina Sarcoidosis Severity, Pain Surgeries, Refractive Systems, Nervous Trauma, Nervous System Vascular Diseases Veterans Vision Visual Analog Pain Scale

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Publication 2009
Administration, Ophthalmic Amyloidosis Antibodies, Antinuclear Cholinomimetics Connective Tissue Diseases Contact Lenses Cornea Dental Caries Diagnosis Dry Eye Eyelids Glaucoma Graft-vs-Host Disease Head Health Personnel Hepatitis C HIV Infections Hypertrophy Lupus Vulgaris Neck Operative Surgical Procedures Parotid Gland Patients Pharmaceutical Preparations Physical Examination Population Group Prescription Drugs Radiotherapy Rheumatoid Arthritis Rheumatoid Factor Sarcoidosis secretion Sjogren's Syndrome SS-B antibodies Tuberculosis Vision Xerostomia

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Publication 2017
Contact Lenses Cornea Dry Eye Microscopy, Confocal Neuralgia Pain Postherpetic Neuralgia Trigeminal Neuralgia Vision
A detailed history was obtained regarding known onset of FECD, family history, ocular and systemic medications, prior history of glaucoma, contact lens wear, ocular trauma and ocular surgeries. All subjects underwent a slit lamp biomicroscopic examination, including determination of conjunctival inflammation, assessment of the cornea for abnormalities, anterior chamber inflammation, iris abnormalities and color, presence of cataract, measurement of intraocular pressure and central corneal thickness.
All investigators were certified on the FECD grading scale by provision and review of a detailed operations manual that included procedures for slit lamp biomicroscopy, a diagram of the grading scale, a photographic example of each grade, and a training video demonstration of the slit lamp biomicroscopic technique (see supplementary material). An investigator meeting at the outset of the study also provided live patient examples of grades on which each investigator submitted their assessment with a requirement that they be within one grading measure on the scale to be certified on the grading.
Every subject received a severity grade for both corneas. A previous classification scheme1 (link) was revised from a 5-step scale to a 6-step scale. The scale was as follows: Grade 0, no guttae; Grade 1, 1–12 central or paracentral non-confluent corneal guttae; Grade 2, more than 12 central/paracentral non-confluent corneal guttae; Grade 3, 1 to 2 mm of confluent central/paracentral corneal guttae at the widest diameter of the confluence after rotating the slit beam and measuring the diameter by narrowing the length of the beam and recording the length in mm; Grade 4, greater than 2 and up to 5 mm; Grade 5, greater than 5 mm of confluent central /paracentral guttae; Grade 6, over 5 mm of confluent central/paracentral guttae with clinically apparent stromal and/or epithelial edema (see Supplementary material for photographic grading guide and Appendix 2 for the grading scale). Subjects with stromal and/or epithelial edema overlying focally dense guttae less than 5 mm in diameter were graded according to the diameter of confluent guttae, with the edema noted separately. Grading was accomplished by scanning the cornea both horizontally and vertically from the center to the limbus by slit lamp biomicroscopy using a narrow slit beam. Eyes that had already had a keratoplasty (either penetrating or endothelial keratoplasty) for FECD were marked as such and assigned a grade of 5. Subjects who underwent penetrating keratoplasty were assigned a grade of 6 if corneal edema was visible on the subject’s pathology specimen. As corneal edema was unable to be evaluated on DSEK pathology specimens, these subjects were assigned a grade of 5.
Grades 4 and higher were considered severe disease. Although grades 2 and 3 could possibly predispose to later progression, the rates and factors for progression to moderate/severe disease are not well defined in the literature18 . Therefore for the purpose of this study, a grade 0 was considered unaffected, grades 1–3 were defined as intermediately affected, and 4–6 were considered affected.
Publication 2012
Cataract Chambers, Anterior Congenital Abnormality Conjunctivitis Contact Lenses Cornea Disease Progression Edema Edema, Corneal Endothelium Eye Eye Injuries Glaucoma Inflammation Iris Keratoplasty Keratoplasty, Penetrating Patients Pharmaceutical Preparations Slit Lamp Slit Lamp Examination Tonometry

Most recents protocols related to «Contact Lenses»

In this prospective, cross-sectional, and comparative investigation, 64 right eyes of 64 participants were evaluated at The University, Medical Faculty, Department of Ophthalmology. The University-Local Ethics Committee approved the study protocol (Protokol Number; 2016-58-09.03). The study was conducted in accordance with the ethical principles of the Declaration of Helsinki, and all of the participants provided written informed consent.
The study groups were selected from patients who have been diagnosed with OSAS by PSG in the Sleep Disorder Laboratory of the Department of Thoracic Medicine but have not yet been treated. The control group was selected from healthy volunteers who applied to the ophthalmology outpatient clinic with presbyopic complaints. Both the Berlin questionnaire (9 (link)) was applied and a complete physical examination was performed by a thoracic medicine specialist (FE) to the participants to be included in the control group to exclude possible OSAS cases. The subjects who had a total score of <2 in the Berlin questionnaire and had no additional ocular and systemic diseases except controlled HT were included in the control group.
The patients who were <18 years old, who had any corneal diseases, ocular diseases requires continued medication (diseases such as glaucoma, uveitis, dry eyes, etc.), previous operation history of the eye in the past 6 months, contact lens use within last 4 weeks, the best corrected visual acuity (BCVA) <20/30 with spherical and cylindrical refraction exceeding ±3 diopter were excluded from the study. Patients who have systemic diseases that may affect the biomechanics of the cornea, such as Sjögren’s Disease, chronic renal failure, diabetes mellitus (DM), liver diseases, chronic obstructive pulmonary diseases, rheumatic, and oncological disorders were also excluded from the study.
The study group was selected according to their AHI value. While mild OSAS cases (AHI <15) were excluded, 32 eyes of 32 patients with moderate to severe OSAS (AHI ≥15; number of moderate case=16 and number of severe case=16) were included in the study (Group 1). The control group was determined as “Group 0” and 32 eyes of 32 patients were recruited in Group 0. Only the right eyes of the subjects were evaluated in both groups.
Publication 2023
Biomechanical Phenomena Chronic Obstructive Airway Disease Contact Lenses Cornea Corneal Diseases Diabetes Mellitus Dry Eye Eye Faculty, Medical Glaucoma Healthy Volunteers Kidney Failure, Chronic Liver Diseases Neoplasms Ocular Refraction Ophthalmologic Surgical Procedures Patients Pharmaceutical Preparations Physical Examination Regional Ethics Committees Sleep Sleep Apnea, Obstructive Thoracic Diseases Uveitis Vision Visual Acuity
A comparative cross-sectional hospital-based study was conducted in a group of 122 consecutive patients with DM and a group of 119 patients with no DM, age-matched by group, who attended the ophthalmology clinic at two tertiary teaching hospitals in Jordan (Jordan University Hospital and King Abdullah University Hospital). All patients were Jordanians of Arab ethnicity.
In the DM group, DM was diagnosed if patients were currently treated with oral hypoglycemic agents, with or without insulin, and if they fulfilled the American Diabetic Association (ADA) Guidelines diagnostic criteria [14 (link)]. In the non-DM group, all patients had glycosylated hemoglobin (HbA1c) <5.8%. Those with a history of ocular surgery involving the ocular surface or nasolacrimal apparatus, eyelid abnormalities (e.g., entropion and trichiasis), acute conjunctivitis, recent use of topical ophthalmic medication (e.g., steroids), and history of wearing contact lenses were excluded.
The study was approved by the Ethics Committee for Medical Research at the Jordan University Hospital and the University of Jordan. It adhered to the tenets of the Declaration of Helsinki. Informed consent for participation was obtained from all participants.
Publication 2023
Age Groups Arabs Congenital Abnormality Conjunctivitis Contact Lenses Diagnosis Entropion Ethics Committees Eyelids Hemoglobin, Glycosylated Hypoglycemic Agents Insulin Lacrimal Apparatus Patients Pharmaceutical Preparations Steroids Trichiasis Vision
OCT images were taken from both eyes at baseline and four hours later. Between the two OCT imaging, one eye was dark adapted and the other eye was kept as control (Fig. 3A,B). The baseline OCT image of both eyes were taken in the dark between 12 p.m. and 1 p.m. to avoid peak disc shedding time as a possible confounder, similar to Lu et al.22 (link). Subjects who wore contact lenses were instructed to remove their contact lenses for the duration of the experiment. Subjects who wore glasses were instructed to remove their glasses during OCT imaging and could elect to wear their glasses during the dark adaptation period over the eye patch if they so chose.

Example of Spectral Domain Optical Coherence Tomography (SD OCT) retinal images obtained (A) B-scan of one subject’s retina through the fovea in the dark adapted/patched eye (left) and unpatched control eye (right), before and after the dark adaptation (DA) period. (B) Side-by-side comparison of the OCT images for the same local retinal region (outlined by the blue rectangles in [A]) for patched and unpatched eyes, before and after the DA period. ILM internal limiting membrane, ELM external limiting membrane, EZ ellipsoid zone, IZ interdigitation zone, RPE retinal pigment epithelium (C) Example of the segmentation performed by the Heidelberg Spectralis software that was used to generate thickness maps for the outer retinal layer. BM basement membrane.

After this initial baseline OCT image was taken, we randomly selected one of each subject’s two eyes and covered that eye with an eye patch that was designed specifically for this study and blocked all potential light from getting through. The eye patch involved taping three layers to the area around the subject’s selected eye: first, a disposable cotton eye pad; second, a flexible sheet of black plastic impenetrable to light; third, a final layer of gauze. After the addition of each eyepatch layer, the subject was asked to shut the other unpatched eye and confirm that no light was visible through or around the eye covering.
The subjects were instructed to keep the eye patch on for four hours in between the two imaging sessions. During this time, the subjects were instructed to stay in a relatively well-lit setting and were instructed to not sleep or spend the patching period in a dark place. These instructions were given to ensure the unpatched eye would be exposed to light for the full duration of the experiment as opposed to the patched eye, which would remain in the dark throughout the experiment. Of the 40 participants, 20 were observed throughout the entirety of the four-hour dark adaptation period and were confirmed to have followed instructions. The remaining 20 gave verbal affirmation they followed instructions. After the dark adaptation period was over, the subjects returned for a second OCT imaging session where both eyes imaged again. The room was kept dark during both imaging sessions to ensure higher quality OCT images. The room was also kept dark during imaging to ensure the patched eye remained dark adapted during post-patching imaging and was not exposed to light until after the patch was removed. The dark adapted eye was imaged immediately after removal of the patch. No follow-up was needed with the subjects after their OCT images were collected.
Publication 2023
Contact Lenses Eyeglasses Gossypium Light Membrane, Basement Microtubule-Associated Proteins Radionuclide Imaging Retina Retinal Pigment Epithelium Sleep Tissue, Membrane Tomography, Optical Coherence
GWAS summary datasets of glycemic traits were obtained from the MRC Integrative Epidemiology Unit (IEU) OpenGWAS database (https://gwas.mrcieu.ac.uk/).14 Consumption of high-sugar diets is linked to obesity, insulin resistance, and hyperglycemia.15 (link),16 (link) Thus, hyperglycemia (HbA1c and fasting glucose), insulin resistance (fasting insulin levels and adiponectin), β-cell dysfunction (fasting proinsulin levels), and the obesity-related trait BMI were selected as components of glycemic traits. These six glycemic traits from different GWASs were analyzed as exposures in this study, including adiponectin (dataset ieu-a-1; n = 39,883),17 (link) BMI (ebi-a-GCST006368; n = 315,347),18 (link) fasting blood glucose (ebi-a-GCST005186; n = 58,074),19 (link) fasting insulin (ieu-b-116; n = 108,557),20 (link) HbA1c (ieu-b-104; n = 46,368),21 (link) and proinsulin levels (ebi-a-GCST001212; n = 10,701).15 (link) Detailed information about each trait is summarized in Table 1. Myopia data integrated by the MRC IEU (ukb-b-6353; “Phenotype: Reason for glasses/contact lenses: For short-sightedness, i.e., only or mainly for distance viewing such as driving, cinema etc, [called ‘myopia’]”) was used as an outcome, with a total of 460,536 participants of European ethnicity. We selected only genetic variants with genome-wide significance (P < 5 × 10−8) for MR analysis.
Publication 2023
ADIPOQ protein, human Blood Glucose Contact Lenses Dietary Sugars Ethnicity Europeans Eyeglasses Genetic Diversity Genome Genome-Wide Association Study Glucose Hyperglycemia Insulin Insulin Resistance Myopia Obesity Pancreatic beta Cells Phenotype Proinsulin
This was a prospective single-arm study. Thirty-eight eyes of 36 patients with iFTMH combined cataract (Grade 2 or above according to the Lens Opacities Classification System III (LOCS III)) [15 (link)] who underwent phacovitrectomy surgery at the Department of Ophthalmology, Tongji Hospital affiliated with Tongji University School of Medicine between October 2021 and September 2022 were enrolled. Exclusion criteria were any ocular diseases other than iFTMH or cataract, contact lens wear, previous ocular surgery, diabetes, and connective diseases. The study was registered with the Chinese Clinical Trial Registry (31/10/2021, ChiCTR2100052554). Moreover, it was approved by the Ethics Committee of the Shanghai Tongji Hospital and followed the principles of the Declaration of Helsinki. All the participants provided written informed consent.
Ocular examinations, including best-corrected visual acuity (BCVA), intraocular pressure (IOP), slit-lamp examination, dilated indirect funduscopic examination and optical coherence tomography (OCT) (Carl Zeiss Meditec, Germany), were performed within 1 week before surgery and 1 day, 7 days, 1 month, and 3 months after surgery.
Corneal endothelial cells were examined using noncontact specular microscopy (SP-1P; Topcon, Japan). This device takes different azimuth shots of a 0.25 mm*0.55 mm corneal endothelial surface. The built-in software can then automatically provide various parameters. The variables included in our study were ECD, hexagonality (HEX), and coefficient of variation (CV).
CD and central corneal thickness (CCT) were provided by the appendix in Pentacam. The study was conducted in a windowless dark room. The ambient light level measured by an illuminometer (LT40; Extech Instruments Corp., Waltham, MA, USA) was approximately 5 lx. Density measurements were represented by standardized gray level units from 0 to 100. Zero represents maximum transparency and 100 represents minimum transparency. The software divided the cornea into four concentric radial areas: 0–2 mm, 2–6 mm, 6–10 mm, and 10–12 mm. Meanwhile, the cornea is divided into three layers, the anterior layer (superficial 120 µm), central layer (between anterior and posterior layers), and posterior layer (depth 60 µm) [16 (link)].
Publication 2023
Cataract Cells Chinese Contact Lenses Cornea Corneal Endothelium Diabetes Mellitus Ethics Committees, Clinical Eye Light Medical Devices Microscopy Operative Surgical Procedures Ophthalmologic Surgical Procedures Ophthalmoscopes Patients Physical Examination Slit Lamp Examination Tomography, Optical Coherence Tonometry, Ocular Visual Acuity

Top products related to «Contact Lenses»

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The Pentacam HR is an advanced corneal topography and anterior segment imaging system. It utilizes a rotating Scheimpflug camera to capture high-resolution, three-dimensional images of the anterior eye. The Pentacam HR provides detailed measurements of the cornea, anterior chamber, and other anterior segment structures.
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The Pentacam is a diagnostic device that captures a 3D image of the anterior segment of the eye. It uses rotating Scheimpflug camera technology to obtain detailed measurements of the cornea, anterior chamber, lens, and iris.
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Tropicamide is a synthetic chemical compound used in ophthalmic applications. It is a pupil dilator that temporarily enlarges the pupil of the eye. Tropicamide is commonly used in eye examinations and diagnostic procedures to facilitate the examination of the inside of the eye.
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The Spectralis is an optical coherence tomography (OCT) imaging device developed by Heidelberg Engineering. It captures high-resolution, cross-sectional images of the retina and optic nerve using near-infrared light. The Spectralis provides detailed structural information about the eye, which can aid in the diagnosis and management of various eye conditions.
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Vigamox is an ophthalmic solution used in the treatment of bacterial conjunctivitis. It contains the active ingredient moxifloxacin hydrochloride, a broad-spectrum fluoroquinolone antibiotic.
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Tropicamide is a synthetic mydriatic and cycloplegic agent used in ophthalmology. It acts as a competitive antagonist of muscarinic acetylcholine receptors, causing pupil dilation and temporary paralysis of the eye's focusing mechanism.
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The IOL Master is a non-contact optical biometry device used to measure various parameters of the eye, including axial length, anterior chamber depth, and corneal curvature. It provides precise measurements that are essential for calculating the appropriate intraocular lens power for cataract surgery.
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The Spectralis HRA is a retinal imaging device developed by Heidelberg Engineering. It utilizes a combination of confocal scanning laser ophthalmoscopy and spectral-domain optical coherence tomography to capture high-resolution images of the retina and its underlying structures.
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The Heidelberg Spectralis SLO/OCT system is a diagnostic imaging device that combines scanning laser ophthalmoscopy (SLO) and optical coherence tomography (OCT) technologies. It is designed to capture high-resolution, three-dimensional images of the eye's structures, including the retina, optic nerve, and anterior segment.
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The Spectralis HRA+OCT is a multimodal imaging device that combines high-resolution fundus imaging with optical coherence tomography (OCT) technology. It allows for the simultaneous acquisition of detailed images of the retina, choroid, and optic nerve.

More about "Contact Lenses"

Contact lenses, also known as corrective lenses or ophthalmic lenses, are medical devices that are worn directly on the surface of the eye.
These versatile lenses serve a variety of purposes, including vision correction, eye protection, and cosmetic enhancement.
They come in a wide range of materials, designs, and prescriptions to cater to the diverse needs and preferences of wearers.
Contact lenses can be used for everyday vision correction, providing a comfortable and convenient alternative to eyeglasses.
They are especially beneficial for individuals with active lifestyles, as they offer unobstructed peripheral vision and reduced interference with various activities.
Contact lenses can also be utilized for specialty applications, such as sports or occupational use, where they can provide enhanced visual performance and protection.
Beyond vision correction, contact lenses can be used for cosmetic purposes, allowing wearers to alter the appearance of their eyes.
This includes enhancing the natural eye color or achieving a more dramatic, expressive look.
Proper fitment, care, and usage are crucial to ensure the safety and comfort of contact lens wearers.
The field of contact lens technology is constantly evolving, with ongoing advancements in materials, designs, and prescriptions.
Tools like the Pentacam HR, Pentacam, and IOL Master play a vital role in the assessment and optimization of contact lens performance.
Additionally, medications like Tropicamide and Vigamox can be used in conjunction with contact lens wear to maintain eye health and comfort.
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Leverage the power of AI to streamline your research, improve reproducibility, and identify the most effective protocols and products.
Discover how PubCompare.ai can transform your contact lens research and unlock new possibilities in this rapidly evolving field.