The mice were housed at the animal facility of the Forschungszentrum Jülich under a controlled specific-pathogen-free (SPF) environment (12/12 h light/dark cycle, humidity maintained around 50%, and a room temperature between 20 and 23 °C). Food, water, and cages were autoclaved prior to entering the SPF area. A maximum of five SOD1*G93A mice and non-transgenic littermates were housed in individually ventilated cages on standardized rodent bedding (Rettenmaier, Rosenberg, Germany). Dried, pelleted standard rodent chow (Altromin, Lage, Germany) as well as tap water were available for the animals ad libitum. After disease onset, nutrition of the animals was ensured using gel pads (Solid Drink® SDST-75, Triple A trading, Tiel, The Netherlands).
Standard rodent chow
Standard rodent chow is a laboratory animal feed product designed to provide a complete and balanced diet for rodents used in research. It is formulated to meet the nutritional requirements of various rodent species, including mice and rats, and is intended to support their health and well-being during scientific investigations.
Lab products found in correlation
8 protocols using Standard rodent chow
Preclinical Model of ALS in Mice
The mice were housed at the animal facility of the Forschungszentrum Jülich under a controlled specific-pathogen-free (SPF) environment (12/12 h light/dark cycle, humidity maintained around 50%, and a room temperature between 20 and 23 °C). Food, water, and cages were autoclaved prior to entering the SPF area. A maximum of five SOD1*G93A mice and non-transgenic littermates were housed in individually ventilated cages on standardized rodent bedding (Rettenmaier, Rosenberg, Germany). Dried, pelleted standard rodent chow (Altromin, Lage, Germany) as well as tap water were available for the animals ad libitum. After disease onset, nutrition of the animals was ensured using gel pads (Solid Drink® SDST-75, Triple A trading, Tiel, The Netherlands).
Male Rat Husbandry and Welfare
All experiments were carried out per the EU directive 2010/63 and were approved by the local animal ethics committee (Lower Saxony State Office for Consumer Protection and Food Safety; AZ 17/2583). All efforts were made to minimize the number of animals used and their suffering.
ApoE-/- Mouse Model for Atherosclerosis
Syndecan-1 Knockout Mouse Protocol
Wistar Rat Housing and Acclimation
Aging and Apolipoprotein E Deficiency in Mice
Mice deficient in the gene encoding apolipoprotein E (ApoE−/−) and wild-type controls (C57BL/6J) were procured from The Jackson Laboratory, located in Bar Harbor, ME, USA. Male mice, aged 12 months, were selected for the experiments. These mice were maintained on a standard rodent chow (Altromin, Lage, Germany). The mice were housed in a carefully controlled environment, featuring a 12 h light/dark cycle, a constant temperature of 22 ± 2 °C, humidity levels maintained at 55 ± 10%, and provided with unrestricted access to both food and tap water.
Housing and Husbandry of Sprague-Dawley Rats
All experiments were carried out in accordance with the EU directive 2010/63 and were approved by the local animal ethics committee (Lower Saxony State Office for Consumer Protection and Food Safety, AZ 18/2874). All efforts were made to minimize the number of animals and their suffering.
Atherosclerosis in Apoe KO Mice
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