Ethyl acetate

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About the product

Ethyl acetate is a clear, colorless liquid solvent commonly used in laboratory applications. It has a characteristic sweet, fruity odor. Ethyl acetate is known for its ability to dissolve a variety of organic compounds, making it a versatile tool in chemical research and analysis.

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Market Availability & Pricing

Ethyl acetate is an active chemical product available through authorized distributors such as Sigma-Aldrich and VWR. It is listed by the Merck Group and suitable for HPLC use with a purity of ≥99.7%. Specific pricing details are not publicly disclosed, and interested customers are advised to contact authorized distributors for organizational and contract pricing information.

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Spelling variants of this product

Ethyl acetate (EtAc) (6 citations) Ethyl (2 citations) Acetates (1 citations) Ethyl α-halogenated acetates (1 citations) Polystyrene in ethyl acetate (1 citations) 1-Ethyl-3-methylimidazolium acetate [emim][Ac] IL (1 citations) Ethyl acetate (EA)-99% (1 citations) Chromatography grade solvents (ethyl acetate and water (1 citations) Methanol Ethyl Acetate NaCl Muller Hinton Agar Muller Hinton Broth (1 citations) Water and ethyl acetate (1 citations)

The spelling variants listed below correspond to different ways the product may be referred to in scientific literature.
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2 598 protocols using ethyl acetate

Synthesis of Substituted Acetophenone Derivatives

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All chemicals and reagents: deferasirox, hydrazine monohydrate, carbon disulfide (CS₂), potassium hydroxide (KOH), substituted acetophenones, acetic acid, sulphuric acid (H₂SO₄), n-hexane, ethyl acetate, diethyl ether, acetone, methanol and ethanol were purchased from Sigma Aldrich.

Shakir S.A., Rashid U., M.a.r.r.y.u.m., Fatima N., Ejaz S.A., Fayyaz A., Ullah M.Z., Saeed A., Khan A., Al Harrasi A, & Mumtaz A. (2025). Exploration of novel triazolo-thiadiazine hybrids of deferasirox as multi-target-directed anti-neuroinflammatory agents with structure–activity relationship (SAR): a new treatment opportunity for Alzheimer's disease. RSC Advances, 15(1), 101-118.

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Quantification of Tocopherol and Tocotrienol

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Ethanol, mEthanol, ethyl acetate, n-hexane (HPLC grade), pyrogallol, sodium chloride, and potassium hydroxide (reagent grade) were purchased from Sigma-Aldrich (Steinheim, Germany). Ethanol (96.2%) for leaf sample saponification was received from SIA Kalsnavas Elevators (Jaunkalsnava, Latvia). Standards of tocopherol homologues (α, β, γ, and δ) (>98%, HPLC) were obtained from Extrasynthese (Genay, France), while tocotrienol homologues (α, β, γ, and δ) (>98%, HPLC) were from Cayman Chemical (Ann Arbor, MI, USA).

Górnaś P, & Symoniuk E. (2025). Tocotrienols in Different Parts of Wild Hypericum perforatum L. Populations in Poland. Molecules, 30(5), 1137.

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Chromatographic Analysis of Fermentation Compounds

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M ethanol and acetonitrile (99% purity) were purchased from Aladdin Co., Ltd. (Shanghai, China). All standards, including lactic acid, propionic acid, caproic acid, ethanol, M ethanol, amyl alcohol, n-propanol, ethyl lactate, ethyl acetate, and ethyl formate, were obtained from Sigma-Aldrich (St. Louis, MO, USA). All other chemicals and reagents used in this study were of analytical grade and were purchased from Sinopharm Chemical Reagent Co., Ltd. (Beijing, China).

Wu Q., Tian S., Zhang X., Zhao Y, & Yu Y. (2025). Identification of Oligopeptides in the Distillates from Various Rounds of Soy Sauce-Flavored Baijiu and Their Effect on the Ester–Acid–Alcohol Profile in Baijiu. Foods, 14(2), 287.

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Palladium-Catalyzed Suzuki-Miyaura Coupling

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9,10-dibromoanthracene (>98%), iodine
(I₂) (>98%), triphenylphosphine palladium (0) (>97%),
copper(I)
iodide (>98%), sodium chloride (>99.5%), magnesium sulfate (>98%),
trimethylsilylacetylene (>98%), hydrochloric acid (1M) triethylamine
(>99%), silica gel, Bis(triphenylphosphine)palladium(II) dichloride
(>98%), 4-Bromo-4’-iodo-1,1’-biphenyl (>98%), potassium vinyltrifluoroborate (>97%)
and
cesium carbonate (>98%) were purchased from TCI America. Zinc acetate
(99.99% trace metals basis), n-butyl lithium (1.6
M in THF), sodium thiosulfate (99.99% trace metals basis), phenylacetylene
(98%), diisopropylamine (DIPA, ≥ 99%), 4-Bromostyrene (97%),
cesium fluoride (≥98%), triphenylphosphine (99%), polyethylene
glycol, osmium tetroxide (2.5 wt % in tert-butanol), tert-butanol (≥99%), dimethylformamide (DMF, anhydrous,
99.8%), dimethyl sulfoxide (DMSO, anhydrous, ≥ 99.9%), ethyl
alcohol (anhydrous, ≥ 99.5%), ethyl acetate (reagent, ≥
99.5%), and oxone were purchased from Sigma-Aldrich. Tetramethylammonium
hydroxide pentahydrate (TMAH, 98%) and oleic acid (OLA, tech., 90%)
were purchased from Alfa Aesar. Solvents used were hexanes, acetone,
toluene, tetrahydrofuran (THF), ethanol, methanol, anisole, tert-butanol, deionized water, dimethylformamide (DMF),
and dichloromethane (DCM).

Lee A.Y., Teferi M., Hernandez F.S., Jain A., Tran T., Wang K., Mani T., Schwartzberg A.M., Tang M.L., Niklas J., Poluektov O.G, & Olshansky J.H. (2025). Tunable Spin Qubit Pairs in Quantum Dot–Molecule Conjugates. ACS Nano, 19(12), 12194-12207.

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Quantification of Tocopherol and Tocotrienol

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Lazdiņa D., Mišina I, & Górnaś P. (2025). Tocotrienols in Eleven Species of Hypericum Genus Leaves. Molecules, 30(3), 662.

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Perovskite Solar Cell Fabrication

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All materials were used as received and were stored in an inert environment prior to use. FAI, MAI, FABr and MABr were purchased from Greatcell Solar Materials. 2PACz (>98%), PbI₂ (99.99%, trace metal basis) and PbBr₂ (>98%) were purchased from TCI Chemicals. DMF (99.8%), DMSO (99.9%, anhydrous) and ethyl acetate (99.8%) were purchased from Sigma-Aldrich. C₆₀ was purchased from SES Research and bathocuproine (BCP) was purchased from Lumtec. Ethanol (<0.1% H₂O) was purchased from Merck Millipore.

Datta K., van Laar S.C., Taddei M., Hidalgo J., Kodalle T., Aalbers G.J., Lai B., Li R., Tamura N., Frencken J.T., Quiroz Monnens S.V., Westbrook R.J., Graham D.J., Sutter-Fella C.M., Correa-Baena J.P., Ginger D.S., Wienk M.M, & Janssen R.A. (2025). Local halide heterogeneity drives surface wrinkling in mixed-halide wide-bandgap perovskites. Nature Communications, 16, 1967.

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Synthesis of Functional Organic Frameworks

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All the chemicals were received from suppliers without further purification unless otherwise noted, including 1,3,5-triformylbenzene (97%, Shanghai Tensus Biotech Co., Ltd.), p-phenylenediamine (97%, Sigma Aldrich), 4,4’-azodianiline (98%, Adamas), 1,3,5-triformylphloroglucinol (97%, Shanghai Tensus Biotech Co., Ltd.), 1,3,5-tris(4-aminophenyl)benzene (97%, Macklin), 2,5-dimethoxy terephthalaldehyde (97%, Sigma Aldrich), 2,2’-bipyridine-5,5’-diamine (98%, Adamas), 1,3,5-tris(4-aminophenyl)benzene (98%, Adamas), terephthalaldehyde (98%, Adamas), benzoic acid (99.5%, Shanghai Lingfeng Chemical Reagent Co., Ltd), 1,4-dioxane (99.5%, Sinopharm Chemical Reagent Co., Ltd), acetic acid (99.8%, Sinopharm Chemical Reagent Co., Ltd), p-toluenesulfonic acid monohydrate (98%, Energy Chemical), benzophenone (95%, Shanghai Apeptide Co., Ltd), L(+)-Tartaric acid (99%, Adamas), Hoveyda-Grubbs II (98%, Adamas), ether (analytical pure, Shanghai Lingfeng Chemical Reagent Co., Ltd), ethyl acetate (95%, Sigma Aldrich), tetrahydrofuran (99%, Shanghai NO.4 Reagent & H.v.chemical Co., Ltd), dichloromethane (99.9%, J&K Scientific), acetone (analytical pure, Sinopharm Chemical Reagent Co., Ltd), ethanol (99.7%, Sinopharm Chemical Reagent Co., Ltd), methanol (analytical pure, Sinopharm Chemical Reagent Co., Ltd), citric acid (98.5%, Sinopharm Chemical Reagent Co., Ltd), N,N-dimethylformamide (analytical pure, Sinopharm Chemical Reagent Co., Ltd), glass fiber (No. 1820-047, Whatman), potassium bromide (99.5%, Innochem), and nickel foam (analytical pure, Thermo Fisher Scientific). Deionized water was made in our laboratory.

Li X., Ji X., Zhang X., Chen X., Li H., Zhang S., Huo F, & Zhang W. (2025). Construction of functional covalent organic framework films by modulator and solvent induced polymerization. Nature Communications, 16, 1223.

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Synthesis and Characterization of Curcumin-Loaded Nanoparticles

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FeCI₂.4H₂O (cat: 220299), FeCI₃.6H₂O (cat: 236489), NH₃·H₂O (28 wt%, cat: 105423), chloroform, cetyltrimethylammonium bromide (CTAB, cat: H6269), ethyl orthosilicate (cat: 131903), ethyl acetate (cat: 650528), methanol (cat: 34860), (3-Mercaptopropyl) trimethoxysilane (MPTMS, cat: 175617), acetone (cat: 179124), cysteamine (cat: 30070), Curcumin (cat: C1386), hydrazine (cat: 225819), buffered saline (PBS, cat: P2272), DAPI (cat: D9542), lipopolysaccharide (LPS, cat: L4391) and BSA (cat: V900933) were purchased from Sigma-Aldrich (St. Louis, MO, USA). CGRPi (BIBN4096), dimethyl sulfoxide (DMSO, cat: HY-Y0320), fluorescein 5-isothiocyanate (FITC, cat: HY-66019) and SYBR Green qPCR Master Mix (cat: HY-K0501A) were obtained from MCE (USA). 0.25% pancreatic enzyme (cat: 25200072) and MEM medium (cat: 11095080) were supplied by Gibco (USA). CCK-8 reagent (cat: E-CK-A362) was purchased from Elabscience (China). Calcein/PI solution (cat: C2015S) was obtained from Beyotime Biotechnology (China). Enzyme linked immunosorbent assay (ELISA) kit (cat: mIC50536-1, mIC50274-1, mIC50300-1 and IC50325-1) was from Shanghai Enzyme-linked Biotechnology (China). DCFH-DA (cat: S0033S) was supplied by Beyotime Biotechnology (China). TRIzol Reagent (cat: 15596018CN) was purchased from Invitrogen (Carlsbad, CA, USA). iScript™ cDNA Synthesis Kit (cat: 1708891) was obtained from Bio-Rad Laboratories (USA).

Zhu Y., Zhang Z., Gao L., Tian Y., Lu X., Jiang Y., Su H., Gu C., Shi C, & Wei L. (2025). Mesoporous silica loaded with calcitonin gene-related peptide antagonist and curcumin alleviate oxidative stress and inflammation in the sciatic nerve. Frontiers in Molecular Biosciences, 12, 1510141.

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Carotenoid and Apocarotenoid Quantification

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Carotenoid standards of 9-cis-neoxanthin (≥97%), violaxanthin (≥90%), lutein (≥99%), α-carotene (≥95%), β-carotene (≥93%), and lycopene (≥90%) were obtained from Sigma Aldrich Chemie GmbH and Zeaxanthin (≥90%) from ChemPur GmbH. Chlorophyll a (≥95%) and b (≥95%) were obtained from Sigma Aldrich Chemie GmbH. Apocarotenoid standards of 6-methyl-5-hepten-2-one (≥99%), β-CC (≥97%) and β-IO (≥96%) were obtained from Sigma Aldrich Chemie GmbH. Dihydroactinidiolide (≥98%) was synthesized by abcr GmbH. β-IO-D₃ (≥95%) used as the internal standard for apocarotenoid quantification was obtained from Eptes. MTBE (≥99.5%) and methanol (≥99.8%) for HPLC analysis were obtained from Fisher Scientific GmbH and acetone for extraction and standard dilutions from Carl Roth GmbH (≥99.9%). Ethylacetate (≥99.9%) for apocarotenoid standard dilutions was obtained from Sigma Aldrich Chemie GmbH and methanol (≥99.9%) for standard dilutions from Fisher Scientific GmbH. Further solvents for carotenoid standard dilutions were dichloromethane (≥99.9%) from Carl Roth GmbH and acetonitrile (≥99.9%) from Fisher Scientific GmbH. BHT (≥99.7%) was obtained from Carl Roth GmbH. The water used for HPLC analysis and extraction was purified by ultrapure water system arium pro (Sartorius).

Rieseberg T.P., Dadras A., Darienko T., Post S., Herrfurth C., Fürst-Jansen J.M., Hohnhorst N., Petroll R., Rensing S.A., Pröschold T., de Vries S., Irisarri I., Feussner I, & de Vries J. (2025). Time-resolved oxidative signal convergence across the algae–embryophyte divide. Nature Communications, 16, 1780.

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Bioactive Compounds from Omani Dates

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Fresh date fruits type “Khalas” at “Tamr” stage were purchased from a local market in Muscat, Oman, in October 2019. Solvents were used as purchased: deionized water (Merck Millipore), dimethylsulfoxide (DMSO), ethanol, ethyl acetate, hexane, and methanol (Sigma-Aldrich), and n-butanol (J.T. Baker). Whatmann precoated Silica gel (60 Å) glass plates were purchased from Merck Millipore. Phosphomolybdic acid (PMA) was obtained from Park Scientific Limited. Silica gel of 60 Å (70–230 mesh) for column chromatography was purchased from Sigma-Aldrich. Dulbecco's phosphate-buffered saline (PBS), serum-free Iscove's modified Dulbecco's medium (IMDM), fetal bovine serum (FBS), penicillin-streptomycin (PS), and trypsin/EDTA were purchased from Life Technologies. Resazurin sodium salt was purchased from Acros Organics. Equipment used in this study are: Cell culture incubator (Haenigsen, Germany), cell culture microplate 96 well F-bottom (Greiner Bio-One, Frickenhausen, Germany), Fluostar Galaxy plate reader (MTX Lab Systems, Virginia, USA), Galaxy 170S Incubator (New Brunswick Scientific, Steinheim, Germany), handheld UV Lamp 254/365 nm UV (UVP, Cambridge, UK), rotary evaporator (BUCHI, Flawil, Switzerland), sonicator (Branson Ultrasonic Corporation, USA), sterile filters of 0.22 μm pore size (Merck Millipore, Darmstadt, Germany), and Vortex-Genie 2 vortexer (Scientific Industries, Inc., Heidelberg, Germany).

Al Alawi R.A., Hoheisel J.D., Alhamdani M.S, & Baqi Y. (2025). Phoenix dactylifera L. (date palm) fruit extracts and fractions exhibit anti-proliferative activity against human pancreatic cancer cell lines. Heliyon, 11(3), e42274.

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