Vivapur 102

Q: How does Vivapur 102 differentiate itself from other microcrystalline cellulose products?

Vivapur 102 by JRS Pharma stands out with its superior compressibility, excellent flow properties, and high purity. Unlike alternatives like Avicel PH101 or Parteck lub MST, Vivapur 102 offers exceptional performance in pharmaceutical formulations, particularly in direct compression tablet manufacturing.

Q: What specific citation details should I use when referencing Vivapur 102 in scientific publications?

When referencing Vivapur 102, include its full product name, manufacturer (JRS Pharma), catalog number, lot number, and specific grade specification. Typical citation format includes: 'Vivapur 102 (Microcrystalline Cellulose, Lot #XXXX, JRS Pharma)' to ensure precise scientific traceability.

Q: What pharmaceutical and industrial systems are compatible with Vivapur 102?

Vivapur 102 is highly versatile, compatible with various pharmaceutical processing systems including direct compression tableting, granulation equipment, and powder blending machinery. It integrates seamlessly with related excipients like Anhydrous Emcompress, Kollidon VA 64, and standard tablet compression technologies.

Q: In what primary research and industrial domains is Vivapur 102 most frequently utilized?

Vivapur 102 is predominantly used in pharmaceutical tablet manufacturing, nutraceutical formulations, and controlled-release drug delivery systems. Its primary applications include direct compression tableting, binding agent in oral solid dosage forms, and as a versatile excipient in both immediate and sustained-release tablet technologies.

Q: What unique scientific innovation is associated with Vivapur 102?

An intriguing aspect of Vivapur 102 is its nano-structural composition, which enables exceptional particle size uniformity and compressibility. This unique microcrystalline cellulose variant has enabled advanced pharmaceutical formulation techniques, particularly in creating more stable and efficiently absorbed tablet designs.

Manufactured by JRS Pharma

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Sourced in Germany, United States

About the product

Vivapur 102 is a microcrystalline cellulose product used as an excipient in pharmaceutical formulations. It is a purified, partially depolymerized cellulose that is produced by hydrolytic degradation of alpha-cellulose. Vivapur 102 is a white, odorless, and tasteless powder.

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Lab products found in correlation

Parteck lub mst, by Merck Group (5 mentions) Anhydrous emcompress, by JRS Pharma (3 mentions) Flowlac 100, by Meggle (3 mentions) Di cafos a150, by Chemische Fabrik Budenheim (3 mentions) Galeniq 721, by BENEO-Palatinit (2 mentions) Lm 40, by L.B. Bohle Maschinen + Verfahren (2 mentions) Vivapur 101, by JRS Pharma (2 mentions) Aerosil 200 pharma, by Evonik (2 mentions) Polyplasdone xl, by Ashland (2 mentions) Acdisol sd 711, by FMC Europe N.V (2 mentions) Eudragit epo, by Evonik (2 mentions) Kollidon va 64, by BASF (2 mentions) Aerosil 200, by Evonik (2 mentions) Nvc 100, by CelluForce (1 mentions) Vivapur cs 4 fm, by JRS Pharma (1 mentions) Tablettose 70, by Meggle (1 mentions) Superstarch 200, by DFE Pharma (1 mentions) Tablettose 80, by Meggle (1 mentions) Supertab 21an, by DFE Pharma (1 mentions) Diclofenac, by Amoli Organics (1 mentions)

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Market Availability & Pricing

VIVAPUR® 102 is a medium-sized microcrystalline cellulose (MCC) grade marketed by JRS Pharma. It combines good flow properties with high compactibility, making it suitable for a variety of directly compressible active pharmaceutical ingredients. The product is compliant with NF, EP, and JP pharmacopeial standards and is typically packaged in 20 kg cartons.

For pricing and purchasing details, please contact JRS Pharma or their authorized distributors directly, as prices may vary based on order quantity and regional factors.

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Spelling variants (same manufacturer)

Vivapur - 2 citations

Similar products (other manufacturers)

Vivapur 102 (by Korsch) - 2 citations

The spelling variants listed below correspond to different ways the product may be referred to in scientific literature.
These variants have been automatically detected by our extraction engine, which groups similar formulations based on semantic similarity.

Product FAQ

How does Vivapur 102 differentiate itself from other microcrystalline cellulose products?

What specific citation details should I use when referencing Vivapur 102 in scientific publications?

What pharmaceutical and industrial systems are compatible with Vivapur 102?

In what primary research and industrial domains is Vivapur 102 most frequently utilized?

What unique scientific innovation is associated with Vivapur 102?

29 protocols using «vivapur 102»

Rivaroxaban Immediate-Release Capsules

2024

Rivaroxaban (Moehs Iberica S.L., Barcelona, Spain). Microcrystalline cellulose (MCC): VIVAPUR^® 102 (JRS Pharma, Rosenberg, Germany). Anhydrous dibasic calcium phosphates (DCPA): PharSQ^® Coarse A 150 and PharSQ^® Fine A 12 (Chemische Fabrik Budenheim KG, Budenheim, Germany). Hydroxypropyl methylcellulose (HPMC): Tylopur^® 605 and Tylopur^® 606 (ShinEtsu SE Tylose GmbH & Co. KG, Wiesbaden, Germany). Sodium lauryl sulfate (SLS) (Sigma-Aldrich Chemie GmbH, Taufkirchen, Germany). Croscarmellose sodium (CCS): Ac-Di-Sol^® SD-711 (FMC BioPolymer, Brussels, Belgium). Magnesium stearate: Ligamed^® MF-2-V (Peter Greven Fett-Chemie, Venlo, The Netherlands). HPMC-based film-coagting system: Aquapolish P (Biogrund GmbH, Huenstetten, Germany). Calcium phosphate-based (DCPA) starter pellets, size M—PharSQ^® Spheres CM (Chemische Fabrik Budenheim KG, Budenheim, Germany). Transparent hard gelatin capsule shells, size “1” (Lutor trading & distribution Ltd., Koeln, Germany). Reference product: Xarelto^® 2.5 mg, 10 mg, 15 mg, 20 mg flilm-coated tablets (Bayer Vital GmbH, Leverkusen, Germany).

Zakowiecki D., Edinger P., Papaioannou M., Wagner M., Hess T., Paszkowska J., Staniszewska M., Myslitska D., Smolenski M., Dobosz J., Garbacz G, & Haznar Garbacz D. (2024). Development and Evaluation of Lactose-Free Single-Unit and Multiple-Unit Preparations of a BCS Class II Drug, Rivaroxaban. Pharmaceutics, 16(11), 1485.

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Evaluating Roll Compaction of Cellulose-Based Powders

2024

Pure Microcrystalline cellulose powder (MCC, Vivapur® 102, JRS Pharma, Germany) and two powder blends containing either MCC or fine powder hydroxypropyl cellulose (HPC, NISSO HPC SSL SFP, Nippon Soda, Japan) as binder and dibasic calcium phosphate anhydrous (DCPA, DI-CAFOS® A60, Chemische Fabrik Budenheim KG, Germany) as filler (Table 1) where evaluated regarding the

ER

at different positions along the roll (Section 2.2.). The detailed investigation of the

ER

kinetics was conducted using MCC (Pharmacel® 102, DFE Pharma, Germany) (Section 2.3.). Blending was performed with 30 rpm for 20 min using a lab-scale blender (LM40, L.B. Bohle Maschinen + Verfahren, Germany). For equilibration, all used materials were stored at 21 °C and 45 % relative humidity. The particle density (

ρ_{0}

) of the individual material was measured using AccuPyc 1330 helium pycnometer (Micromeritics, Norcross, USA) and the

ρ_{0}

of the powder blends was estimated using the weighted harmonic mean of the individual

ρ_{0}

.Table 1

Materials and formulations investigated in roll compaction.

Table 1

Formulations	Proportion / %
MCC	100
MCC + DCPA	30 + 70
HPC + DCPA	10 + 90

Lück M., Klinken-Uth S, & Kleinebudde P. (2024). Kinetics of elastic recovery in roll compaction. International Journal of Pharmaceutics: X, 8, 100303.

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Amlodipine and Hydrochlorothiazide Formulation

2024

In this experimental research, amlodipine besylate and hydrochlorothiazide (Sigma-Aldrich (St.louis, MO, USA)) were chosen as model drugs. Microcrystalline cellulose (MCC, Vivapur 102) was purchased from JRS Pharma (Patterson, NY, USA), while mannitol (Mannitum) and polyvinyl pyrrolidone were supplied by Hungaropharma Zrt. (Budapest, Hungary). Distilled water was used as the granulating binder.

Mahmoud A.A., Hassan A.A., Dobó D.G., Ludasi K., Janovák L., Regdon G J.r., Csóka I, & Kristó K. (2024). Investigation of the Electrokinetic Potential of Granules and Optimization of the Pelletization Method Using the Quality by Design Approach. Pharmaceutics, 16(7), 848.

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Lyophilized Lysozyme Enzymatic Activity

2023

Lyophilized LYS from chicken egg white (Mw: 14.3 kDa) (MedChemExpress, Monmouth, NJ, USA) was used as a model protein. Lyophilized Micrococcus lysodeikticus (Sigma-Aldrich, St. Louis, MO, USA) was used as Gram-positive bacteria to investigate LYS enzymatic activity. Sodium dodecyl sulphate (SDS) (Molar Chemicals Ltd., Budapest, Hungary) was used as counterion for HIP and sodium hydroxide and hydrochloric acid (Ph. Eur.) as pH adjusters. Tween 80^® (polysorbate 80) (Merk KgaA, Darmstadt, Germany), PEG 400 (polyethylene glycol 400) (Molar Chemicals Ltd., Budapest, Hungary), and Miglyol 812^® (medium-chain triglycerides) (Sasol Germany GmbH, Witten, Germany) were used in preparation of liquid SEDDS. Neusilin^® UFL2 (magnesium aluminometasilicate) (Fuji Chemical Industries Co., Ltd. Kamiichi, Nakaniikawa, Toyama, Japan), Syloid^® 244 FP, and Syloid^® AL-1 FP (Grace Davison, Worms, Germany) were used as solid carriers in preparation of solid SEDDS. Vivapur 102^® (microcrystalline cellulose) and Vivasol^® (croscarmellose sodium) (JRS PHARMA GmbH & Co. KG, Rosenberg, Germany) were used in tablet formulation as diluent and disintegration agents, respectively. Salts used to prepare the phosphate buffer as well as all the other reagents were of analytical grade.

Šahinović M., Hassan A., Kristó K., Regdon G J.r., Vranić E, & Sovány T. (2023). Quality by Design-Based Development of Solid Self-Emulsifying Drug Delivery System (SEDDS) as a Potential Carrier for Oral Delivery of Lysozyme. Pharmaceutics, 15(3), 995.

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Formulation Development of Pancreatic Enzyme Tablets

2023

Pancreatin (from porcine pancreas) EMPROVE^® ESSENTIAL USP was from Merck KGaA (Darmstadt, Germany). Anhydrous dibasic calcium phosphate, DCPA (DI-CAFOS^® A150), tribasic calcium phosphates, TCPs (TRI-CAFOS^® 500 and TRI-CAFOS^® 200-7) were produced by Chemische Fabrik Budenheim KG (Budenheim, Germany). Low-substituted hydroxypropyl cellulose, L-HPC (LH-11) was provided by ShinEtsu (Wiesbaden, Germany). Microcrystalline cellulose, MCC (VIVAPUR^® 102 was from JRS Pharma (Rosenberg, Germany), Magnesium stearate (Ligamed^® MF-2-V) was supplied by Peter Greven Fett-Chemi (Venlo, The Netherlands).

Zakowiecki D., Edinger P., Hess T., Paszkowska J., Staniszewska M., Romanova S, & Garbacz G. (2023). Effect of Compaction Pressure on the Enzymatic Activity of Pancreatin in Directly Compressible Formulations. Pharmaceutics, 15(9), 2224.

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